Step 1: Ensure your cream cheese is softened to room temperature for easier mixing.
Step 2: Grate both the extra-sharp cheddar and mild cheddar cheeses from blocks. Avoid pre-shredded cheese for the best texture.
Step 3: Thoroughly drain the diced pimentos. You can press them in a fine-mesh sieve or pat them dry with paper towels to remove as much liquid as possible.
Step 4: In a large mixing bowl, combine the freshly grated sharp cheddar and mild cheddar cheeses.
Step 5: Add the well-drained pimentos to the cheese mixture.
Step 6: Add the softened cream cheese to the bowl.
Step 7: Spoon in the Duke's mayonnaise.
Step 8: Season the mixture with onion powder, garlic powder, Worcestershire sauce, cayenne pepper, and freshly ground black pepper.
Step 9: Using a sturdy spatula or spoon, mix all ingredients until well combined and creamy. Be careful not to overmix; some texture from the grated cheese is desirable.
Step 10: Taste and adjust seasonings as necessary. You may want to add more pepper, Worcestershire, or cayenne to suit your preference.
Step 11: Transfer the pimento cheese to an airtight container.
Step 12: Refrigerate for at least 2-4 hours, or preferably overnight, to allow the flavors to meld and deepen. Serve chilled or at room temperature.