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A golden-brown slice of autumn vegetable lasagna with butternut squash showing layers of pasta and roasted vegetables.

Autumn Vegetable Lasagna with Butternut Squash

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A comforting, creamy vegetarian lasagna featuring roasted butternut squash, fresh sage, and a silky béchamel sauce.

  • Total Time: 90 minutes
  • Yield: 8 servings 1x

Ingredients

Scale

1 large butternut squash (about 3 lbs), peeled and cubed
2 tablespoons olive oil
12-15 lasagna noodles (no-boil or pre-cooked)
4 cups whole milk
1/2 cup unsalted butter
1/2 cup all-purpose flour
2 cups fresh spinach, chopped
15 oz ricotta cheese
2 cups shredded mozzarella cheese
1 cup grated Parmesan cheese
2 tablespoons fresh sage, finely chopped
1/2 teaspoon ground nutmeg
Salt and black pepper to taste

Instructions

Step 1: Preheat your oven to 400°F (200°C). Toss the cubed butternut squash with olive oil, salt, and pepper on a baking sheet. Roast for 25-30 minutes until tender and slightly caramelized.
Step 2: While the squash roasts, melt butter in a large saucepan over medium heat. Whisk in the flour and cook for 1-2 minutes to create a roux. Slowly whisk in the milk, stirring constantly until the sauce thickens. Remove from heat and stir in the sage, nutmeg, and a pinch of salt.
Step 3: In a small bowl, mix the ricotta cheese with half of the Parmesan and the chopped spinach. Mash about half of the roasted butternut squash into the ricotta mixture for extra flavor.
Step 4: Reduce oven heat to 375°F (190°C). Spread a thin layer of béchamel sauce in the bottom of a 9x13 inch baking dish. Place a layer of noodles on top.
Step 5: Spread a layer of the ricotta-squash mixture over the noodles, followed by a layer of roasted squash cubes and a sprinkle of mozzarella. Repeat the layers until all ingredients are used, ending with a layer of béchamel and a generous topping of mozzarella and the remaining Parmesan.
Step 6: Cover with foil and bake for 30 minutes. Remove the foil and bake for another 15-20 minutes until the top is bubbly and golden brown. Let it rest for 10 minutes before slicing.

Notes

For a gluten-free version, use gluten-free lasagna sheets. Ensure your béchamel roux uses a 1:1 ratio of butter and flour.

  • Prep Time: 30 minutes
  • Cook Time: 60 minutes
  • Category: Main Dishes & Savory Recipes
  • Cuisine: Italian-American

Nutrition

  • Serving Size: 1 Slice
  • Calories: 420 kcal
  • Sugar: 7g
  • Sodium: 680mg
  • Fat: 18g
  • Saturated Fat: 10g
  • Unsaturated Fat: 6g
  • Trans Fat: 0g
  • Carbohydrates: 48g
  • Fiber: 5g
  • Protein: 19g
  • Cholesterol: 55mg